The Neurology Minute® podcast delivers a brief daily summary of what you need to know in the field of neurology, the latest science focused on the brain, and timely topics explored by leading neurologists and neuroscientists. From the American Academy of Neurology and hosted by Stacey Clardy, MD, PhD, FAAN, with contributions by experts from the Neurology® journals, Neurology Today®, Continuum®, and more.

The pitfall is waiting for very frequent attacks before offering prevention. Open this for a concise update on anti-CGRP evidence, mood comorbidity, children with disabling migraine, and why preventive therapy may be reasonable even when the attack count still looks modest.

Migraine prevention should be discussed when headache disrupts work, school or family life, even if attacks are not frequent. A practical takeaway is to stop escalating acute medication alone and to use current guidance when considering earlier anti-CGRP or other preventive therapy.

Worth opening if your unit sees stroke. Late-presenting patients without large vessel occlusion may still enter a reperfusion pathway when imaging shows salvageable tissue, and adjunct intra-arterial alteplase after thrombectomy comes with selection, protocol and audit requirements.

Adjunct dexamethasone should not be assumed to improve confirmed HSV encephalitis simply because it appears safe. In this phase III trial, 26-week outcomes, mortality, and discharge timing were similar to acyclovir alone, and the findings should not be extrapolated to undifferentiated encephalitis.
